Sense of security is one of the most important features in an urban place. Concept of sense of urban security has been always at the center of attentions in understanding urban studies. The principle objective of this research is assessment of effective factors on the sense of urban security by application of Decision-Making Trial and Evaluation Laboratory (DEMATEL) as a comprehensive and integrated method. This study first conducted the survey based on literature review to identify major factors on the sense of urban security in Tehran metropolitan. Researchers show that eight main criteria are important in assessment of sense of urban security in Tehran metropolitan. According to the result, material welfare (sustainable income and employment) and far from poverty, unemployment and justice, equality and non-discrimination are factors which have the maximum effect on other factors. Based on the result of research, four factors belong to the cause group and four factors are the effect group.